Arrhythmia Data Sonification - Revision history

Vsmercola at 13:06, 26 August 2020

2020-08-26T13:06:13Z

Vsmercola at 21:21, 15 December 2019

2019-12-15T21:21:31Z

Vsmercola: /* Further Reading / Viewing */

2019-12-15T21:19:44Z

‎Further Reading / Viewing

Vsmercola at 21:16, 15 December 2019

2019-12-15T21:16:44Z

Vsmercola: /* End Result */

2019-12-15T21:16:12Z

‎End Result

Vsmercola at 21:13, 15 December 2019

2019-12-15T21:13:28Z

Vsmercola at 21:12, 15 December 2019

2019-12-15T21:12:44Z

Vsmercola at 21:12, 15 December 2019

2019-12-15T21:12:31Z

Vsmercola at 21:12, 15 December 2019

2019-12-15T21:12:11Z

Vsmercola at 01:13, 14 December 2019

2019-12-14T01:13:44Z

@@ Line 159: / Line 159: @@
 * [https://sonic-pi.net/ Sonic Pi] - the open-source live-coding synth I used to make the music for this project.
 * [https://en.wikipedia.org/wiki/Long_QT_syndrome Long QT Syndrome (Wikipedia Article)] - this is the syndrome that my father is currently working to treat with Mex2A.
 [[Category: Advisor:Manzo]]
 [[Category:Algorithmic, Interactive, & Electro-acoustic Compositions]]
 [[Category:Electronic Music Composition (3620)]]

@@ Line 146: / Line 146: @@
 == End Result ==
-The first result of the project only had a simple drum pattern as a base loop and was used as a proof-of-proof-of-concept. I sent the results to my father and his staff and he said that they really liked it. After talking with him about it, I added a simple bass to the base loop, which made it sound slightly better.
+The first result of the project only had a simple drum pattern as a base loop and was used as a proof-of-proof-of-concept. I sent the results to my father and his staff; he said that they really liked it. After talking with him about the sounds that I made, I added a simple bass to the base loop and a sound to indicate the start of a measure, which made it sound slightly better.
 This video below shows the data sonification in order from the 11.111uM dose to the control 0uM dose.
@@ Line 153: / Line 153: @@
 <mediaplayer>File:Arrhythmia-Data-Sonification-0-to-11.mp4</mediaplayer>
-Would nightcore, speedcore, and/or extratone music that varies with an arrhythmic heartbeat sound good? I don't think so. However, I can say for certain that this project was a very effective way to use sound to compare the the different doses of Mex2A when treating Long QT3 syndrome.
+Would nightcore, speedcore, and/or extratone music that varies with an arrhythmic heartbeat sound good? I don't think so. However, I can say for certain that this project was a very effective way to compare the the different doses of Mex2A when treating Long QT3 syndrome.
 == Further Reading / Viewing ==

@@ Line 158: / Line 158: @@
 * [https://www.gnu.org/software/octave/ GNU Octave] - the open-source scientific programming language I used to analyze the data for this project.
 * [https://sonic-pi.net/ Sonic Pi] - the open-source live-coding synth I used to make the music for this project.
 == Post-Mortem ==

@@ Line 160: / Line 160: @@
 == Post-Mortem ==
-This part will be updated once I finish continuing this project over break. If my father's paper on Mex2A is published, I'll definitely leave a link here. Stay tuned!
+This part will be updated once I finish continuing this project over break. If my father's paper on Mex2A and Long QT3 syndrome is published, I'll definitely leave a link here. Stay tuned!
 [[Category: Advisor:Manzo]]
 [[Category:Algorithmic, Interactive, & Electro-acoustic Compositions]]
 [[Category:Electronic Music Composition (3620)]]

@@ Line 153: / Line 153: @@
 <mediaplayer>File:Arrhythmia-Data-Sonification-0-to-11.mp4</mediaplayer>
-Would nightcore, speedcore, and/or extratone music that varies with an arrhythmic heartbeat sound good? I don't think so. However, I can say for certain that this project was a very effective tool for using sound to compare the control and expected-dosage results of Mex2A.
+Would nightcore, speedcore, and/or extratone music that varies with an arrhythmic heartbeat sound good? I don't think so. However, I can say for certain that this project was a very effective way to use sound to compare the the different doses of Mex2A when treating Long QT3 syndrome.
 == Further Reading / Viewing ==

@@ Line 148: / Line 148: @@
 The first result of the project only had a simple drum pattern as a base loop and was used as a proof-of-proof-of-concept. I sent the results to my father and his staff and he said that they really liked it. After talking with him about it, I added a simple bass to the base loop, which made it sound slightly better.
-This video below shows the data sonification from the 11.111uM dose to the control 0uM dose.
+This video below shows the data sonification in order from the 11.111uM dose to the control 0uM dose.
 <mediaplayer>File:Arrhythmia-Data-Sonification-11-to-0.mp4</mediaplayer>
-This video below shows the data sonification from the control 0uM dose to the 11.111uM dose.
+This video below shows the data sonification in order from the control 0uM dose to the 11.111uM dose.
 <mediaplayer>File:Arrhythmia-Data-Sonification-0-to-11.mp4</mediaplayer>

@@ Line 16: / Line 16: @@
 To turn the heartbeat data into music intervals, I first opened the file in GNU Octave (open-source MATLAB alternative). I first wanted to find the average interval of the 11uM dose beats, because I wanted the average interval's corresponding BPM to be scaled to 120 BPM. After recording the timestamps of all of the important peaks, I made a new array of intervals of unit milliseconds. With those intervals, I could convert the intervals' inverse, in Hz (1 cycle per second). I then converted the intervals' Hz to BPM (beats per minute) by multiplying by 60.
-I figured out that the heart cells when given the 11uM dose could beat at about 43.885 BPM normally. In music terms, that tempo is the faster end of "grave". I decided from here that I could normalize the interval BPM's by dividing each value by the average. From here, it was rinse and repeat for the other graphs - The interval data for 3.703uM, 1.2345uM, 0.4115uM, 0.1271uM, and 0uM were all normalized with the same 43.885 BPM value. The remaining data ,100uM and 33.333uM, were not used because there wasn't any pulse on the same intensity as the 11uM dose.
+I figured out that the heart cells when given the 11uM dose could beat at about 43.885 BPM normally. In music terms, that tempo is the faster end of "grave". I decided from here that I could normalize the interval BPM's by dividing each value by the average. From here, it was rinse and repeat for the other graphs - The interval data for 3.703uM, 1.2345uM, 0.4115uM, 0.1271uM, and 0uM were all normalized with the same 43.885 BPM value. The remaining data, 100uM and 33.333uM, were not used because there wasn't any pulse on the same intensity as the 11uM dose.
   %{

@@ Line 4: / Line 4: @@
 == Introduction ==
 Before working with music, there is some important preliminary background information to go over.
@@ Line 13: / Line 12: @@
 [[File:Mex2A graph.PNG|800px|center|Series of graphs of the results, from 100uM to 0uM left to right.]]
-My father sent me a large spreadsheet that, when graphed, produced the results of the graphs above. These show the results of human heart cells with Long QT3 syndrome given different dose amounts of Mex2A, in micromolar. The graphs' X-axes show the measured time in milliseconds, with measured intervals spaced roughly 30 ms apart. The graphs' Y-axes show the measured intensity - when the heart cells beat, the intensity goes up. One can tell from the graphs that the 100uM dose and 33.333uM dose results do not show any peaks, but the 11.111uM dose shows strikingly regular peaks denoting a heartbeat. When I saw this data, I thought would be neat to make "music" where each peak represented a music measure's bar line, and the tempo of the song would increase or decrease depending on how fast or slow the heart cells beat, respectively.
+My father sent me a large spreadsheet that, when graphed, produced the results of the graphs above. These show the results of human heart cells with Long QT3 syndrome given different dose amounts of Mex2A, in micromolar. The graphs represent the direct electrical activity of heart muscle cells that is related to the surface ECG reading. rightmost graph with the title "0" is the control data, without any Mex2A dose (0 uM). As the graphs progress from right to left, the graph's peaks become more and more regular until the 11.111uM dose - this dose shows strikingly regular peaks denoting a heartbeat. When I saw this data, I thought would be neat to make "music" where each peak represented a music measure's bar line, and the tempo of the song would increase or decrease depending on how fast or slow the heart cells beat, respectively.
 To turn the heartbeat data into music intervals, I first opened the file in GNU Octave (open-source MATLAB alternative). I first wanted to find the average interval of the 11uM dose beats, because I wanted the average interval's corresponding BPM to be scaled to 120 BPM. After recording the timestamps of all of the important peaks, I made a new array of intervals of unit milliseconds. With those intervals, I could convert the intervals' inverse, in Hz (1 cycle per second). I then converted the intervals' Hz to BPM (beats per minute) by multiplying by 60.
-I figured out that the heart cells when given the 11uM dose could beat at about 43.885 BPM normally. In music terms, that tempo is the faster end of "grave". I could normalize the interval BPM's by dividing each value by the average. From here, it was rinse and repeat for the other graphs - The interval data for 3.703uM, 1.2345uM, 0.4115uM, 0.1271uM, and 0uM were all normalized with the same 43.885 BPM value.
+I figured out that the heart cells when given the 11uM dose could beat at about 43.885 BPM normally. In music terms, that tempo is the faster end of "grave". I decided from here that I could normalize the interval BPM's by dividing each value by the average. From here, it was rinse and repeat for the other graphs - The interval data for 3.703uM, 1.2345uM, 0.4115uM, 0.1271uM, and 0uM were all normalized with the same 43.885 BPM value. The remaining data, (100uM and 33.333uM) were not used because there wasn't any pulse on the same intensity as the 11uM dose.
   %{

← Older revision		Revision as of 01:13, 14 December 2019
Line 162:		Line 162:
	== Post-Mortem ==		== Post-Mortem ==
	This part will be updated once I finish continuing this project over break. If my father's paper on Mex2A is published, I'll definitely leave a link here. Stay tuned!		This part will be updated once I finish continuing this project over break. If my father's paper on Mex2A is published, I'll definitely leave a link here. Stay tuned!
		+
		+	[[Category: Advisor:Manzo]]
		+	[[Category:Algorithmic, Interactive, & Electro-acoustic Compositions]]
		+	[[Category:Electronic Music Composition (3620)]]